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MK-4827 br Methods br Results br Discussion
2019-06-24
Methods Results Discussion Analyses of basal syndecan-1 expression showed differences in syndecan-1 levels as well as staining pattern for this proteoglycan in the breast cancer cell lines that were employed. Different localization of syndecan-1 have been found in previous studies showing l
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br Approval statement br Role of
2019-06-24
Approval statement Role of the funding source Conflict of interest Acknowledgments Introduction Osteosarcoma (OS) is the most common malignancy of bone, mainly affecting children, adolescents and young adults. According to the American Cancer Society, 750–900 new cases of OS are diagn
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AICAR phosphate Aside from distinct technical approaches use
2019-06-24
Aside from distinct technical approaches used, the well-established RANKL and RANK expression patterns in the bone further substantiates the expression patterns defined in the current study of OS. RANKL and RANK play major roles in bone metabolism due to the critical role of this pathway in osteocla
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br Genetic basis for atrial standstill br Genetic
2019-06-24
Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an
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We discussed in our report the potential
2019-06-24
We discussed in our report the potential to improve vaccine acceptance and increase demand for OPV by engaging people within communities to deliver health education. Our analysis focused on all reported sources of health education within a community—ie, not only traditional leaders but also the loca
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La Brev ssima relaci n de
2019-06-24
La Brevíssima relación de la destruyción de las Indias de fray Bartolomé de las Casas, fechada el 8 de diciembre de 1542, se publica en el año 1552 (“… fue rogado e importunado que destas postreras pusiesse algunas por brevedad por escrito”). Finalmente es condenada en 1660 por el Tribunal de la Inq
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Contraria a la publicidad representativa propia de
2019-06-24
Contraria CHIR-98014 what la publicidad representativa, propia de regímenes anteriores al capitalismo, como el feudalismo y la monarquía, centrada en la legitimación del sujeto del poder y expendedora de un “aura” a su autoridad, ligada al atributo de la persona (vestidos, emblemas), sus gestos y su
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GSK1838705A structure Podemos seguir con ejemplos espigados
2019-06-24
Podemos seguir con ejemplos espigados: el plan de instrucción pública del peruano Hipólito Unanue, tras la obligada crítica al antiguo régimen, preveía estudios de “humanidades y filosofía en lengua vulgar entrando después en el estudio del latín los que lo hubieran menester”. En Venezuela se quiso
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Es as como se establece la relaci
2019-06-24
Es así como se establece la relación entre los dos relatos: la novela histórica es parte de la novela policíaca y ambas tienden al mismo fin trágico, la muerte de su respectivo héroe. Al respecto, conviene hacer ciertas acotaciones sobre el término de “héroe”. Si bien en este último pasaje citado de
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Myeloid sarcoma can be observed as a de novo malignancy
2019-06-24
Myeloid sarcoma can be observed as a de novo malignancy (without leukemic presentation in peripheral blood and bone marrow), during the course of acute myeloid leukemia (AML), affecting 2.5–9% of all AML patients, myelodysplastic syndromes (MDS) or myeloproliferative neoplasms (MPNs, both chronic my
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br We have concerns about
2019-06-24
We have concerns about both the accuracy and underlying rationale of Eugene Richardson and colleagues\' Comment about the “Ebola suspect\'s dilemma”. The authors quote a nosocomial infection rate of “around 25%” for individuals admitted to Ebola treatment facilities without Ebola virus disease. Ho
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Lubiprostone Introduction Atrial fibrillation AF is a highly
2019-06-24
Introduction Atrial fibrillation (AF) is a highly prevalent atrial arrhythmia that affects approximately 10% of individuals older than 75 years of age and tends to increase in prevalence with advancing age [1–3]. Although AF itself is not life threatening, it is a risk factor for stroke, and the AF
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LQT can have numerous clinical manifestations ranging from n
2019-06-21
LQT1 can have numerous clinical manifestations, ranging from no symptoms to sudden cardiac death, which reflects the heterogeneity in channel dysfunction. Mutation type, location, and even a patient׳s ethnic background, age, and gender are critical factors that affect the pathophysiology of the dise
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Eligio Mar a Ancona Castillo naci
2019-06-21
Eligio María Ancona Castillo nació en la ciudad de Mérida, el 1° de diciembre de 1836. Después de cursar los estudios elementales en la escuela de su padre, inició los cursos preparatorios en el Seminario Conciliar de San Ildefonso. Más tarde se inscribió en la Universidad del Estado para iniciar la
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In our opinion environmental pollution should be
2019-06-21
In our opinion, environmental pollution should be considered as a common risk factor for both dementia and schizophrenia. Studies are warranted to test this hypothesis, and if confirmed, the clinical implications could be of great importance for public and mental health. Future research, including l
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