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AQP protein expression was determined by
2020-02-25

AQP4 protein expression was determined by Western blot analysis. Briefly, protein samples (50μg) from brains or astrocytes were separated by 12% SDS–polyacrylamide gel electrophoresis and transferred to nitrocellulose membranes. The membranes were reacted with a rabbit polyclonal antibody against AQ
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br Bipartite graph br Algorithm for CFC br
2020-02-25

Bipartite graph Algorithm for CFC Error detection rate and overhead evaluation Test results and discussion For verifying the proof in sphingosine receptor from the perspective of practice, this section brings tests and analysis based on the onboard computer (OBC) of the in-service ZDPS-1
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br Collagens as new drivers
2020-02-25

Collagens as new drivers of zebrafish tissue regeneration Contrary to mammals, zebrafish possess very high regeneration capacities and thereby represent a versatile model to study tissue and organ regeneration. Adult fish can fully reconstruct their brain, spinal cord, retina, kidney, liver, panc
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Ki16425 br Materials and methods br
2020-02-25

Materials and methods Acknowledgements SD was supported by a pre-doctoral research fellowship from the Flanders Agency for Innovation and Entrepreneurship (VLAIO-Flanders, Belgium). YB is supported by a postdoctoral fellowship from Research Foundation Flanders (FWO, Belgium). We thank Isabelle
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br Introduction Benzanthrone BNZ is a
2020-02-25

Introduction Benzanthrone (BNZ) is a dye intermediate used in the synthesis of number of polycyclic vat and disperse dyes. It has been detected as an environmental pollutant in urban ambient air particulates, originating from furnace effluents, municipal refuge, wood and coal combustion and autom
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In present study we measured the
2020-02-25

In present study, we measured the methylation and pmsf levels of CDKL2 in HCC tissues and cell lines. Meanwhile, correlations between the methylation and mRNA expression, clinicopathological features were evaluated. Materials and methods Results Discussion DNA methylation is a heritable e
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Two isoforms of intracellular ER ER and ER after binding
2020-02-25

Two isoforms of intracellular ER, ERα, and ERβ, after binding to estrogens and translocate to the nucleus, activate some transcription factors and signaling pathways. The deregulation of estrogenic pathways can elevate transcriptional activity contributed to the development of cancer. Expression of
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It has previously been established that
2020-02-25

It has previously been established that DDRs play an important role in collagen regulation in at least two distinct ways: (1) activation of DDRs by collagen results in up-regulation of the matrix metalloproteinases, which results in cleavage and degradation of the ECM20., 21., [22] and (2) ll-37 of
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One of the most frequent gene alterations in
2020-02-24

One of the most frequent gene alterations in MM is methylation of the p15 and p16 genes in the 5′ upstream region. P15 and p16 proteins are Embelin regulators involved in the inhibition of transition from G1 to S phase. Frequencies of p15 or p16 gene methylation up to 32% and 53%, respectively, hav
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The V V process of the FPGA development
2020-02-24

The V&V process of the FPGA development includes equivalence checking (Huang and Cheng, 1998, Huang et al., 2000, Kuehlmann and Krohm, 1997, Kuehlmann et al., 1995, Burch et al., 1994) as well as the simulation techniques. The equivalence checking can prove that two given designs have the same funct
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br Materials and methods br Results br Discussion
2020-02-24

Materials and methods Results Discussion We initially found that ISL, a natural product with a linear scaffold (2-propenone), is able to inhibit CK2 (IC50 = 17.3 μM). Then we have investigated the inhibitory potential of a novel series of compounds with linear scaffolds by combining fragmen
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The presence of a vicious cycle established between
2020-02-24

The presence of a “vicious cycle” established between tumor proliferation and paratumor osteolysis plays a crucial role in the development of primary bone tumors [53]. Cancer cells produce soluble factors that activate directly or indirectly via osteoblasts, osteoclast differentiation and maturation
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The Penicillium strain used in this work was isolated
2020-02-24

The Penicillium strain used in this work was isolated from Atlantic forest soil and previously screened as lipase producer (Tauk-Tornisielo et al., 2005). The immobilization was previously evaluated using hydrophobic supports, i.e. agarose based butyl-(But), phenyl-(Phe) and octyl-Sepharose (Oct), a
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GPR also known as EBI
2020-02-24

GPR183 (also known as EBI2) is a Gαi-coupled seven-transmembrane chemotactic receptor. It is highly expressed on follicular B cells, CD4+ dendritic cells (DCs), and CD4+ T cells but is downregulated on germinal center (GC) aromatase inhibitor in secondary lymphoid organs and controls cell migration
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Several studies have described the
2020-02-24

Several studies have described the role of NP in vRNP nuclear export. For example, leptomycin B (LMB), an inhibitor of the CRM1 nuclear export signal (NES) binding domain (Kudo et al., 1999), inhibits nuclear export of vRNP and NP, but not NEP or M1, in virally infected or transfected ac 723 (Elton
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