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Behaviors were compared between saline
2021-06-10
Behaviors were compared between saline and amphetamine pre-treatment groups at 24h and 2 weeks following the last treatment, or between pre-treatment groups that received vehicle or ASV-30 infusions, using separate two-way ANOVAs. Significant effects were analyzed further using Student–Newman–Keuls
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Previous studies from our laboratory in CD
2021-06-10
Previous studies from our laboratory in CD1 mice using the incisional postoperative pain model have shown that the incision induces significant mechanical postoperative hyperalgesia lasting between 7 and 10days, with peak effect between 4h-2days (Cabañero et al., 2009a, Cabañero et al., 2009b, Campi
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In we studied normal rational varieties X of complexity
2021-06-10
In [1] we studied normal, rational -varieties X of complexity one, where the latter means that X comes with an effective torus action such that holds. We showed that for affine X with and at most log terminal singularities, the iteration of Cox rings is possible. In the present article, we charac
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jnk inhibitor receptor Some studies have integrated the use
2021-06-10
Some studies have integrated the use of cloud computing with user interfaces in the domain of our proposal (i.e. UI). In [24] the authors work with Android devices to achieve more flexibility in the user interfaces by making use of information about the environment (for example, with an ambient ligh
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This study was aimed to assess a number of
2021-06-10
This study was aimed to assess a number of esterase activities, namely erythrocyte AChE, plasma BuChE and BeChE, and serum PON1 towards a number of substrates, as well as the major genetic polymorphisms of BCHE and PON1in a cohort of greenhouse workers exposed to low toxicity pesticides under an int
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Therefore the SPH algorithm in
2021-06-10
Therefore, the SPH algorithm in AUTODYN-3D™ was used to simulate the experiment in Ref. [5] to verify the credibility of the numerical simulation method by results that could be measured accurately. Then the verified numerical simulation method was used to simulate BAD generated by RHA subjected to
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cAMP mediated signaling pathways are important for maintaini
2021-06-10
cAMP-mediated signaling pathways are important for maintaining metabolic homeostasis, and the effects of the glucagon/catecholamine–cAMP–PKA axis on energy balance have been well documented [20]. For example, Cy5 maleimide (non-sulfonated) of the PKA 2β regulatory subunit (RIIβ) in mice leads to inc
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br Structure of USP Schematic representation
2021-06-10
Structure of USP7 Schematic representation of the USP7 domain architecture is shown in Fig. 3B. USP7 is a 135 kDa protein that consists of seven domains, including the N-terminal TRAF-like (Tumor necrosis factor Receptor–Associated Factor) domain, followed by the catalytic core domain and the fiv
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The contribution of local ETA and ETB receptors towards heat
2021-06-10
The contribution of local ETA and ETB receptors towards heat hyperalgesia induced by inoculation of XC tumor FSLLRY-NH2 in the paw of mice has been demonstrated by Baamonde and colleagues (Baamonde et al., 2004). Furthermore, using neuropathic and inflammatory nociception models, several studies ha
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We had earlier reported that collagen fibers
2021-06-10
We had earlier reported that collagen fibers with intact native banded structure were occasionally observed in the kinase-deficient, membrane-anchored DDR2 ECD (DDR2/-KD) samples; however, in our DDR1/ECD and DDR2/ECD samples, observation of native banded structure of collagen was far more infrequen
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molar calculator E is a classical initiator
2021-06-09
E1 is a classical initiator protein and, as such, plays several roles in the initiation and catalysis of viral DNA synthesis. E1 must first recognize a specific segment of the viral molar calculator known as the “origin of DNA replication”, or “ori” for short. For most PV types examined to date, th
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MK-3207 HCl Introduction Determining how genes function toge
2021-06-09
Introduction Determining how genes function together as biological systems is a defining challenge of the genomic era. While genome sequences reveal the DNA blueprint of organisms, deciphering how this blueprint leads to biological function is challenging due in large part to the complexity of prot
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The only reported synthesis of the aminobicyclic core of
2021-06-09
The only reported synthesis of the aminobicyclic core of is based on bis-alkylation of a 4-amino-5,6-dihydroxypyrmidine with dibromoethane. The likelihood of poor regiocontrol/reactivity in utilizing such a transformation for the synthesis of compounds with a substituent on the dioxinyl ring led us
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The primary aim of this study was to evaluate DAPK
2021-06-09
The primary aim of this study was to evaluate DAPK methylation as a tumor marker which is not only detected in the primary tumor but also in the serum of patients. We used matched pre-operative serum samples to determine the correlation of tumor and serum results. Despite an equal methylation freque
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Many filarial species harbor an endosymbiotic bacterium of t
2021-06-09
Many filarial species harbor an endosymbiotic bacterium of the genus Wolbachia. A recent investigation of Wolbachia distribution in 35 filarial species including 28 species and 7 genera and/or subgenera have shown that 37% of them harbor Wolbachia (Ferri et al., 2011). In filarial nematodes, Wolbach
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