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Knowledge about adipose tissue has evolved considerably over
2023-12-19
Knowledge about adipose tissue has evolved considerably over the last two decades. Always been described as an inert tissue having the function of stocking lipids, adipose tissue is now recognized as a real organ with both metabolic and endocrine functions secreting various factors into the blood to
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BTL-104 The regulation of gene expression
2023-12-19
The regulation of gene expression by glucocorticoids can be mediated either by the canonical mechanism that involves the interaction of the glucocorticoid receptor (GR), a transcription factor activated by the hormone, with glucocorticoid response element (Ye et al., 2007), or by the non-canonical m
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MADS box proteins are combinatorial transcription factors in
2023-12-19
MADS box proteins are combinatorial transcription factors in that they often derive their regulatory specificity from other DNA binding or accessory factors. In many cases, the cofactor with which MADS box proteins interact specifies which genes are regulated, when they are regulated and if these ge
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We report here the first study
2023-12-19
We report here the first study on the inhibitory effects of the organic nitrates – on human erythrocyte GR. The previous reports by Becker et al., investigated other nitro derivatives (including arylizoalloxazines) by using Beutler’s method, monitoring GR inhibition. Data of show inhibition of hGR
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To our knowledge this study collected all
2023-12-19
To our knowledge, this study collected all published research of occurrence of Cy5 TSA in water, sediment and aquatic organisms of typical Lakes by 2017 according to http://www.cnki.net/, https://xue.glgoo.net/, http://xueshu.baidu.com/, and http://www.sciencedirect.com/. Some information of Lakes a
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In our previous study we found that
2023-12-19
In our previous study we found that the total activity of aldehyde dehydrogenase in cancer WP1130 of RCC is at the same level as in normal renal tissue [10]. These findings are similar to our results in serum patients with renal cancer. There is no significant difference between ALDH activity in se
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In earlier experiments on snails a behavioral
2023-12-18
In earlier experiments on snails, a behavioral model was employed of certain food rejection to study the mechanisms of the reconsolidation of long-term associative memory. It was found that conditioned food stimuli (reminder) presentation, combined with injections of NMDA glutamate receptor antagoni
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However for a molecular target to
2023-12-18
However, for a molecular target to be useful in AD, it must rescue behavioral as well as biochemical insults. In humans, AD memory impairments typically declare themselves initially as disruption of episodic memory and consolidation of new memories, eventually progressing to global cognitive decline
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Recent studies have indicated that V ATPase activity negativ
2023-12-18
Recent studies have indicated that V-ATPase activity negatively regulates vacuolar fusion in vivo[17]. Since we have demonstrated that the pah1Δ hiv protease inhibitors have a more acidic vacuolar pH than the WT cells, and the genes involved in the pump activity are upregulated compared to WT, the p
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Along with the improvement of the cadmium transport
2023-12-18
Along with the improvement of the cadmium transport from roots to aerial tissues, as is required for phytoremediation, over-expression of PtoHMA5 also led to the excessive accumulation of cadmium in leaves that was harmful to plant growth and physiological performance. Thus, detoxification of the he
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Another heroic set of studies combining retrodialysis
2023-12-18
Another heroic set of studies combining retrodialysis with electrophysiological recording at two distinct brain sites further indicated that the estradiol-induced increase in auditory-evoked firing in NCM also enhanced the selectivity of auditory-evoked responses in the downstream sensorimotor nucle
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Placental cells also express P aromatase CYP
2023-12-18
Placental cells also express P450 aromatase (CYP19A1, encoded by CYP19A1). In the placenta, this enzyme requires an external source of androgens, provided by the adrenal gland of the fetus, to form estrogen. The fetal adrenal gland produces dehydroepiandrosterone (DHEA) [9] and, in the placenta, it
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br Material and methods br
2023-12-18
Material and methods Results Discussion Asparagine, arginine, leucine, methionine, and glutamine are the essential NHS-SS-Biotin australia for cancer cells and intensively investigated for the development of selective targeted therapeutics. Among them, asparagine depleting bacterial enzyme
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Since the beginning of s
2023-12-18
Since the beginning of 1990s, more than 17,000 papers about physiological relevance of antioxidants have been published according to data from web of science. Based on the available literature, it seems that assessing the antioxidant potential of food by means of in vitro assays or solely epidemiolo
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Cathepsin G Inhibitor I br Acknowledgments br Protein microa
2023-12-18
Acknowledgments Protein microarrays were developed to provide miniaturized high-throughput tools to study protein function, Cathepsin G Inhibitor I and post-translational modifications. Just a few years ago, the seminal work performed in Stuart Schreiber's laboratory at Harvard University () a
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