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DENV has also been shown
2018-10-24
DENV has also been shown to counteract IFN signaling in the infected cells, mainly through the expression of NS5 and NS4B (Munoz-Jordan et al., 2005; Ashour et al., 2009; Morrison et al., 2013). We indeed observed lessened ISG induction in the infected raltegravir potassium but not in the uninfecte
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The Douay group reported that when adult HSC derived
2018-10-24
The Douay group reported that when adult HSC-derived mature erythroblasts were peripherally injected into the donor, at least half could survive in circulation for as long as 26 days (Giarratana et al., 2011). However, these in vitro expanded mature erythroblasts did not accumulate in a specific org
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The capacity to delay cell cycle progression at
2018-10-24
The capacity to delay cell-cycle progression at the G1/S transition is central to tumor suppression by RB proteins, predominantly via interaction with, and inhibition of, the E2F family of S-phase transcriptional activators. In Drosophila, the role of Rbf proteins in cell-cycle regulation is conside
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In addition binding and POLR G dependent expression
2018-10-24
In addition, binding and POLR3G-dependent expression was detected for a subset of tRNA genes, predicted miRNA AC008738.2, VTRNA1–3, and ribonucleoproteins RNY1, RNY4, and RNY5, with currently unclear function in the regulation of pluripotency. Strong binding of POLR3G to numerous tRNAs without trans
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Here using hNPCs derived from RTT patient iPSCs as
2018-10-24
Here, using hNPCs derived from RTT patient iPSCs as an example, we have shown that our method of hypoxia-mediated rapid astrocytic differentiation of hNPCs can be applied to functional analysis of patient-derived astrocytes. We revealed that MECP2 MT astrocytes diminish the soma size, neurite outgro
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A very specific case of the problem solved in this
2018-10-24
A very specific case of the problem solved in this paper was dealt with in paper [10]. Namely, it was proved that the characteristic function corresponding to the solution of a system of piecewise-linear stochastic differential equations is an entire function. The author of [10] studies the systems
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As can be seen from Fig
2018-10-24
As can be seen from Fig. 1, introducing two additional solid solution layers leads to modes with the propagating character of atomic motions in the cmv layers emerging in the frequency range from Е1ТО-GaN to А1ТО-AlN. The frequencies of these modes lie in the TO range from А1ТО-Al0.5Ga0.5N to Е1ТО-A
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The half widths of the three reflections in the vicinity
2018-10-24
The half-widths of the three reflections in the vicinity of these reflection angles allow monitoring the average size of ordered BC regions. The intensity of the first GDC-0068 Supplier increases for the disintegrated BC film, and its half-width decreases, indicating a greater orientational ordering
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Analysts may empirically check if the outcome variable
2018-10-24
Analysts may empirically check if the outcome variable has an ICC that BKM 120 is distinguishable from zero, as introduced briefly above. Even those favoring a priori specification of how the model will account for clustering, coauthor or reviewer suggestions may warrant an empirically-informed res
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The majority of adult deaths occurred in males as expected
2018-10-24
The majority of adult deaths occurred in males, as expected. However, more than half of the adult female deaths occurred in a health facility. Sex of the adult decedents was significantly associated with the place of death. Consistent with previous studies in Ethiopia (Anteneh et al., 2013), in Japa
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Study based on a goal driven survey
2018-10-24
Study 2, based on a goal driven survey supplemented Study 1 and shows two mechanisms that influence CSR consumer satisfaction, one directly and the other indirectly through the mediation of brand attitude. The results confirm the direct influence of CSR on customer satisfaction, and Baron and Kenny\
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It is with much pride that I am able
2018-10-24
It is with much pride that I am able to write the foreword to our first issue of the (SAJCE) published by Elsevier. The Journal was originally published by the South African Institution of Chemical Engineers. I remember receiving copies of the journal by post in the late 1990s as an undergraduate s
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br Empirical application public health services demand br Co
2018-10-23
Empirical application: public health services demand Combining public health services supply and demand Under the zip inhibitor that demand is correctly estimated, it is possible to assess whether there are imbalances between supply and demand in the delivery of health services and to check w
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pathway Our finding that Hydralazine inhibits renal fibrosis
2018-10-23
Our finding that Hydralazine inhibits renal fibrosis due to the induction of active DNA de-methylation begs the question of why such a beneficial effect has gone unnoticed for a drug that has been used for more than 50years. In this regard, existing data on a potential reno-protective effect of Hydr
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Our finding that low BRCA expression was
2018-10-23
Our finding that low BRCA1 cathepsin inhibitors was not associated with basal-like subtype or worse survival is consistent with the lack of evidence that somatic loss of BRCA1 contributes meaningfully to sporadic breast cancer. Only homozygous, not heterozygous, Brca1 knockout mice develop breast c
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