• Growing concerns about the robustness and reproducibility

  2018-10-23

  

  Growing concerns about the robustness and reproducibility of neuroimaging results have recently garnered unanimous attention (Abi-Dargham and Horga, 2016; Blackford, 2017; Lerch et al., 2017; Poldrack et al., 2017). The quest for pragmatically usable biomarkers calls for the rigorous assessment of t

• The decrease in Ab levels is undoubtedly caused

  2018-10-23

  

  The decrease in Ab levels is undoubtedly caused by general deterioration of the immune response, which is well documented, not only in terms of decreased CD4+ T-cell counts but also in proliferative responses (Imami et al., 2013; Lewis et al., 2014). Here, we sought to quantify and characterize peri

• Samples were biofunctionalized using plasma electrolytic oxi

  2018-10-23

  

  Samples were biofunctionalized using plasma electrolytic oxidation on a custom-made laboratory setup. Details regarding the experimental setup can be found in [1]. Plasma electrolytic oxidation is an electrochemical process, which drives uniform growth of the titanium oxide (TiO2) layer on the surfa

• The values of the projectile aerodynamic and physical parame

  2018-10-22

  

  The values of the projectile aerodynamic and physical parameters required to compute the aerodynamic jump associated with the projectile in-bore tilt are tabulated in Table 2. Referring to Fig. 1 in order to compute the lateral throw-off associated with the 5.56 mm CT projectile tilt, the following

• br From protoBIM to quantumBIM In the search

  2018-10-22

  

  From protoBIM to quantumBIM In the search for finding the key to solve the above specification dilemma Hyperbody has developed a program based on the dynamic principles of swarm behavior (Fig. 6). The hrg (Hyperbody Research Group) software organizes the behavior of points in space, while these p

• br Results The results showed a correlation between demograp

  2018-10-22

  

  Results The results showed a correlation between demographic groups and method of choice or perception of graphic quality. Age was a factor in preference of tool use (hand, digital, or a hand/digital hybrid approach) in the creation of design sketches (Χ2 (10)=25.411, p=.005) and for illustrative

• Because the rate of intestinal perforation is high with

  2018-10-22

  

  Because the rate of intestinal perforation is high (> 30%) with chemotherapy, some authors suggest that surgical resection could prevent this complication and improve patient outcomes. Nevertheless, some authors argue that PCL originating from intestinal lymphoid tissue should be treated as a system

• br Hypothesis of mtDNA instability in Warburg effect One of

  2018-10-22

  

  Hypothesis of mtDNA instability in Warburg effect One of the most commonly adopted hypothesis to explain the association between human mtDNA instability and Warburg effect in human cancers is oxidative damage and its vicious cycle. As we know, oxidative DNA damage has been demonstrated to play an

• br Treatment Although complete surgical resection provides t

  2018-10-22

  

  Treatment Although complete surgical resection provides the best outcome and is the ultimate goal of therapy, the addition of chemotherapy has changed treatment from surgery alone to a multimodal approach. Chemotherapy alone, and later with a good surgical technique, has improved survival in pati

• Xenobiotic metabolism is a commonly encountered

  2018-10-22

  

  Xenobiotic metabolism is a commonly encountered problem during development of new drug candidates thus applicable also for potential toxicants in food [4,9,25,28,34,92]. By far the most important class of metabolic enzymes are cytochrome P450 (CYPs) monooxygenase drug metabolizing phase I enzymes bu

• bupropion hydrochloride cost Beside its efficacy in the trea

  2018-10-22

  

  Beside its efficacy in the treatment of refractory epilepsy, the ketogenic diet has been suggested to be useful in the therapy of neurodegenerative and neuromuscular diseases including AD, Parkinson’s disease, amyotrophic lateral sclerosis and mitochondrial disorders [34]. The ketogenic diet is like

• br Acknowledgements This work is financially

  2018-10-22

  

  Acknowledgements This work is financially supported by the NSFC grant of 21475030, the S&T Research Project of Anhui Province15czz03109, the National 10000 Talents-Youth Top-notch Talent Program. Introduction Despite several advancement in medical sciences, cardiovascular disease (CVD) remain

• The top polyurethanes identified by our approach and were st

  2018-10-22

  

  The top polyurethanes identified by our approach, 134, 212 and 223, were structurally related comprising the monomers: (poly[1,6-hexanediol/neopentyl glycol/di(ethyleneglycol)-alt-adipic acid] diol (PHNGAD), 4,4′-methylenebis(phenyl isocyanate) (MDI) and 1,4-butanediol (BD)); (poly[1,6-hexanediol/ne

• Limitations for neural stem progenitor

  2018-10-22

  

  Limitations for neural stem/progenitor cells include in vitro expansion for transplantation as well as loss of capacity to differentiate when expanded in vitro which limit their ability to form functional grafts (Svendsen et al., 1996) with lack of generation of specific cell types such as dopaminer

• br Materials and methods br Statistical analysis Data are pr

  2018-10-22

  

  Materials and methods Statistical analysis Data are presented as mean±standard error of the mean (SEM) of at least three independent experiments. Comparisons were performed using a two-tail unpaired t-test or a one sample t-test (real time PCR). Results Discussion In this work we have i

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