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Our experiments demonstrate that serotonin activates the las
2018-10-23
Our experiments demonstrate that serotonin activates the las quorum sensing pathway, which leads to greater infectivity of P. aeruginosa, however continued experimentation with Pseudomonas infection and serotonin can help to fully elucidate this complex interplay. Our mouse model was limited due to
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Although HCV RNA and genotype testing rates have
2018-10-23
Although, HCV RNA and buy Ramelteon testing rates have improved in recent years and are similar to those reported for HCV positive Veterans and Kaiser Permanente members in the United States (95%) and higher than for primary care in Canada and United States (47.0% to 60.9%), there is a further need
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Regarding the anti viral response
2018-10-23
Regarding the anti-viral response occurring during ZIKV infections, few reports using different cell types led to different observations. ZIKV AS (H/PF/2013) has been shown to induce an innate antiviral response in primary human skin fibroblasts characterized by the upregulation of TLR3, DDX58 (RIG-
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The in vivo replication kinetics of
2018-10-23
The in vivo replication kinetics of ZIKV in natural human infections remains elusive. The neurotropic nature of ZIKV has been evidenced by mouse experiments (Cugola et al., 2016) and clinical investigations (Carteaux et al., 2016). Our necropsy data from two animals demonstrate that the contemporary
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Specifically in this study the significant
2018-10-23
Specifically in this study, the significant prediction of metabolic syndrome for ESCC mortality was observed to be largely mediated by hyperglycemia and dyslipidemia. In support of this view, a previous meta-analysis of 17 observational studies documented that males with diabetes may have a modestly
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The nuclear factor one NF family consists of four
2018-10-23
The nuclear factor one (NF1) family consists of four site-specific transcription factors (NfiA, NfiB, NfiC, and NfiX) that play a large role in the development of a number of organs systems such as the lung and pyruvate dehydrogenase kinase (Grunder et al., 2002; Harris et al., 2015; Hsu et al., 20
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br Funding The work was financially supported by the by
2018-10-23
Funding The work was financially supported by the by grants from the Ministry of Science and Technology of the People\'s Republic of China (2014AA020524), the Special Research Fund of Ministry of Health for Non-Profit Sector (201302010), the National Nature Science Foundation (81302507), the Scie
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Growing concerns about the robustness and reproducibility
2018-10-23
Growing concerns about the robustness and reproducibility of neuroimaging results have recently garnered unanimous attention (Abi-Dargham and Horga, 2016; Blackford, 2017; Lerch et al., 2017; Poldrack et al., 2017). The quest for pragmatically usable biomarkers calls for the rigorous assessment of t
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The decrease in Ab levels is undoubtedly caused
2018-10-23
The decrease in Ab levels is undoubtedly caused by general deterioration of the immune response, which is well documented, not only in terms of decreased CD4+ T-cell counts but also in proliferative responses (Imami et al., 2013; Lewis et al., 2014). Here, we sought to quantify and characterize peri
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Samples were biofunctionalized using plasma electrolytic oxi
2018-10-23
Samples were biofunctionalized using plasma electrolytic oxidation on a custom-made laboratory setup. Details regarding the experimental setup can be found in [1]. Plasma electrolytic oxidation is an electrochemical process, which drives uniform growth of the titanium oxide (TiO2) layer on the surfa
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The values of the projectile aerodynamic and physical parame
2018-10-22
The values of the projectile aerodynamic and physical parameters required to compute the aerodynamic jump associated with the projectile in-bore tilt are tabulated in Table 2. Referring to Fig. 1 in order to compute the lateral throw-off associated with the 5.56 mm CT projectile tilt, the following
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br From protoBIM to quantumBIM In the search
2018-10-22
From protoBIM to quantumBIM In the search for finding the key to solve the above specification dilemma Hyperbody has developed a program based on the dynamic principles of swarm behavior (Fig. 6). The hrg (Hyperbody Research Group) software organizes the behavior of points in space, while these p
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br Results The results showed a correlation between demograp
2018-10-22
Results The results showed a correlation between demographic groups and method of choice or perception of graphic quality. Age was a factor in preference of tool use (hand, digital, or a hand/digital hybrid approach) in the creation of design sketches (Χ2 (10)=25.411, p=.005) and for illustrative
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Because the rate of intestinal perforation is high with
2018-10-22
Because the rate of intestinal perforation is high (> 30%) with chemotherapy, some authors suggest that surgical resection could prevent this complication and improve patient outcomes. Nevertheless, some authors argue that PCL originating from intestinal lymphoid tissue should be treated as a system
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br Hypothesis of mtDNA instability in Warburg effect One of
2018-10-22
Hypothesis of mtDNA instability in Warburg effect One of the most commonly adopted hypothesis to explain the association between human mtDNA instability and Warburg effect in human cancers is oxidative damage and its vicious cycle. As we know, oxidative DNA damage has been demonstrated to play an
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