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The majority of adult deaths occurred in males as expected
2018-10-24
The majority of adult deaths occurred in males, as expected. However, more than half of the adult female deaths occurred in a health facility. Sex of the adult decedents was significantly associated with the place of death. Consistent with previous studies in Ethiopia (Anteneh et al., 2013), in Japa
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Study based on a goal driven survey
2018-10-24
Study 2, based on a goal driven survey supplemented Study 1 and shows two mechanisms that influence CSR consumer satisfaction, one directly and the other indirectly through the mediation of brand attitude. The results confirm the direct influence of CSR on customer satisfaction, and Baron and Kenny\
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It is with much pride that I am able
2018-10-24
It is with much pride that I am able to write the foreword to our first issue of the (SAJCE) published by Elsevier. The Journal was originally published by the South African Institution of Chemical Engineers. I remember receiving copies of the journal by post in the late 1990s as an undergraduate s
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br Empirical application public health services demand br Co
2018-10-23
Empirical application: public health services demand Combining public health services supply and demand Under the zip inhibitor that demand is correctly estimated, it is possible to assess whether there are imbalances between supply and demand in the delivery of health services and to check w
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pathway Our finding that Hydralazine inhibits renal fibrosis
2018-10-23
Our finding that Hydralazine inhibits renal fibrosis due to the induction of active DNA de-methylation begs the question of why such a beneficial effect has gone unnoticed for a drug that has been used for more than 50years. In this regard, existing data on a potential reno-protective effect of Hydr
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Our finding that low BRCA expression was
2018-10-23
Our finding that low BRCA1 cathepsin inhibitors was not associated with basal-like subtype or worse survival is consistent with the lack of evidence that somatic loss of BRCA1 contributes meaningfully to sporadic breast cancer. Only homozygous, not heterozygous, Brca1 knockout mice develop breast c
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The most important risk factor for HCC
2018-10-23
The most important risk factor for HCC is chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection (). The risk of HCC is increased 5- to 15-fold in chronic HBV carriers () and 11.5- to 17-fold in HCV-infected patients (). In addition, epidemiological studies have shown that chronic infl
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With the discovery of the phospholipase A receptor PLAR
2018-10-23
With the discovery of the phospholipase A receptor (PLAR) and thrombospondin type-1 domain-containing 7A (THSD7A) as target antigens in 80% of patients with primary membranous nephropathy clinical and experimental research as well as patient management can be better adapted to the pathophysiology of
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With fecal DNA Chen and colleagues
2018-10-23
With fecal DNA, Chen and colleagues reported that the overall composition of the microbiota differed between 47 CRA cases and 47 colonoscopically normal, age- and sex-matched controls (Chen et al., 2013). Nominally significant differences in relative abundance, not adjusted for multiple comparisons,
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estrogen receptor Although rRBD vaccination alleviated pneum
2018-10-23
Although rRBD vaccination alleviated pneumonia and decreased viral load in the rhesus macaque upon challenge with MERS-CoV in this study, it did not prevent the infection of MERS-CoV completely. The data should be interpreted with some cautions. First, the rhesus macaque models to mimic MERS-CoV inf
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In this report we screened peripheral blood
2018-10-23
In this report, we screened peripheral blood mononuclear cells (PBMCs) approximately 2.5years post infection (PI) from an individual who demonstrated cross-clade ADCC and neutralizing Ab responses (Piantadosi et al., 2009; Bosch et al., 2010). Memory B cells that expressed B cell receptors (BCRs) th
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br Competing Interests br Author Contributions br
2018-10-23
Competing Interests Author Contributions Acknowledgments This review is supported by the Mitchell Center for Neurodegenerative Diseases and John Sealy Memorial Fund. We are grateful to the Kayed lab members for their helpful suggestions. Introduction Recent developments in cancer immuno
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As these pathogenic pathways are probably not specific
2018-10-23
As these pathogenic pathways are probably not specific for HIV infection but relevant to any situation of chronic immune activation, including aging, and given the frequency of these comorbidities, these observations are of general interest. It is for instance striking that HIV infection and the aut
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erbb2 inhibitor We have demonstrated that a direct inhibitor
2018-10-23
We have demonstrated that a direct inhibitor on InhA can retain the outstanding profile of isoniazid and considering the DMPK parameters of both compounds the antitubercular effect is achieved at similar exposures of free drug proving our initial erbb2 inhibitor and overcoming resistances mediated
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Second when talking about risk associated
2018-10-23
Second, when talking about risk associated with alcohol consumption, it makes little sense to use words such as safe. Rather, risk needs to be examined for each disease outcome separately because pathways and risk differ from disease to disease, and the same amount of alcohol may be associated with
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