• Macrophages are now regarded as prominent players in metabol

  2018-11-05

  

  Macrophages are now regarded as prominent players in metabolic disorder and associated diseases. Their sub-populations (M1 and M2 macrophages) may have either deleterious or protective functions towards inflammatory regulation depending on certain conditions of various inflammatory microenvironments

• br Materials and Methods br Results br Discussion In

  2018-11-05

  

  Materials and Methods Results Discussion In the present population-based study, we assessed the relationship between pre-diagnostic Treg to tTL ratios and future cardiovascular events using a highly specific epigenetic assay for the quantification of T cell subsets. After a median follow-up

• Interestingly GRK down modulation similarly inhibited tumor

  2018-11-05

  

  Interestingly, GRK2 down-modulation similarly inhibited tumor growth of breast tumor cell lines-derived xenografts irrespective of their p53 status, suggesting that the ability of GRK2 to modulate tumor development in vivo is independent of the p53 status or, alternatively, that it has a double-edge

• br Numerous studies have reported H the first discovered

  2018-11-05

  

  Numerous studies have reported H19, the first discovered long non-coding RNA (lncRNA), to have key regulatory functions in tumor development and progression (). This paternally imprinted gene is located close to the telomeric region of chromosome 11p15.5 that frequently harbors genetic alterations

• br Materials and methods br Results and discussion br

  2018-11-05

  

  Materials and methods Results and discussion Conclusions The centre composite design of response surface methodology was successfully used in optimising the reaction conditions for biodiesel production from waste vegetable oil in the presence of GDC-0994 heterogeneous catalyst prepared from

• br Conclusions We implemented the scattering

  2018-11-05

  

  Conclusions We implemented the scattering-integral-based full waveform inversion (FWI) concept presented in Schumacher et al.  [11] in form of the modularized software package ASKI—Analysis of Sensitivity and Kernel Inversion. In EPI-001 to monolithic software realizations of FWI, which are stil

• oxytocin receptor Regarding the internal consistency of the

  2018-11-05

  

  Regarding the internal consistency of the total scale, estimated through the Cronbach׳s alpha, the obtained results suggest minimal adequacy of the scale according to Nunnaly׳s criteria [26]. We also attempted to study the discriminant capacity of the QSAR in discriminating OSAS subjects from healt

• Conclusively both questionnaires were found to be psychometr

  2018-11-05

  

  Conclusively, both questionnaires were found to be psychometrically valid instruments that allow a screening about adolescents׳ and parents׳ perceptions about sleep, according to three dimensions and respective nine sub-dimensions, materialized in a model of education which includes sleep behavioral

• br Method br Result br Discussion Sleepiness is

  2018-11-05

  

  Method Result Discussion Sleepiness is a physiological phenomenon, regulated by two processes: processes S (homeostatic) and C (circadian) [28]. The process S (homeostatic) depends on sleep and wakefulness; the need for sleep increases as wakefulness continues and the process C (circadian)

• The neurological mechanisms underlying our findings

  2018-11-05

  

  The neurological mechanisms underlying our findings may be related to the key role played by the hippocampus on the human ability to orient in spatial surroundings [32]. Sleep deprivation before learning affects activity in the medial temporal lobe (MTL) reducing its ability to encode new declarativ

• To demonstrate the function of our portable transmittance re

  2018-11-05

  

  To demonstrate the function of our portable transmittance reader, we collected data from our ALT assay over a wide range of ALT concentrations in human serum. For each concentration, we tracked the light transmission through four read zones in two assays. To run each ALT assay, we placed the assay i

• br Introduction The DNA chip microarray is widely used in

  2018-11-05

  

  Introduction The DNA chip (microarray) is widely used in genotyping and gene expression analysis as a tool capable of detecting two or more genes simultaneously [2,16,19,20]. However, it is suitable for use only in research since the detection limit, dynamic range and detection time are insuffici

• In this study we are unable to

  2018-11-03

  

  In this study we are unable to estimate the contribution of environmental factors to schizophrenia risk. We interpret the overall higher risk in MZ twins (in all our results) as indication of the importance of genetic factors according to the classical twin model (Boomsma et al., 2002). Furthermore,

• We found that SpGlpO interacts with a

  2018-11-03

  

  We found that SpGlpO interacts with a wide range of host glycans with the strongest binding to those that are commonly found as O-linked glycans of protein glycosylation and as lactoceramides/gangliosides. In addition, asialo-GM1 contains the core GalNAcβ1-4Gal suggesting that SpGlpO is an alternati

• Z-YVAD-FMK Images were recorded on a GE

  2018-11-03

  

  Images were recorded on a GE ImageScanner III system. The gels were analyzed with the ImageMaster 2D Platinum software, and automatic spot matching in conjunction with detailed manual checking of the spot finding, to identify proteins in both the NECs and TECs. The quality of the gels was verified b

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